منابع مشابه
Characterization of cDNA encoding human placental anticoagulant protein (PP4): homology with the lipocortin family.
A cDNA library prepared from human placenta was screened for sequences encoding the placental protein 4 (PP4). PP4 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Partial amino acid sequence information from PP4-derived cyanogen bromide fragments was used to design three oligonucleotide pr...
متن کاملExpression of human recombinant lipocortin I in a wheat-germ cell-free system and Xenopus oocytes. Lipocortin is not secreted.
Lipocortin I has been presumed to be synthesized and secreted in response to glucocorticoids yet the amino acid sequence of lipocortin I reveals no signal sequence typically necessary for proteins to enter the secretory pathway. The translocation of lipocortin I across membranes was analyzed in a cell-free system and in Xenopus oocytes. Based on the published sequence, the cDNA of human lipocor...
متن کاملMolecular cloning of mouse placental lactogen cDNA.
We have isolated a cDNA clone for the 23-kDa mouse placental lactogen II (mPL-II) from a phage lambda gt11 expression library containing cDNA synthesized from BALB/c placental RNA. Translation in vitro of placental mRNA selected by hybridization to the mPL-II cDNA clones yields a 26-kDa polypeptide that is the size of the expected precursor protein and that is immunoprecipitated with anti-mPL-I...
متن کاملNucleotide sequence of lupin leghemoglobin I cDNA.
The nucleotide sequence of -full length leghemoglobin (Lb) cDNA " clone -from yellow lupin (Lupinus luteus) is presented. The amino acid sequence deduced -from the nucleotide sequence is in accor— "* dance with known ammo acid sequence of lupin Lb I e;:cept position 79 where GLn is -found instead o-f GILI. Several conserved * sequence mot i -fs, found also in other Lb genes C13 are underlined "...
متن کاملHuman somatostatin I: sequence of the cDNA.
RNA has been isolated from a human pancreatic somatostatinoma and used to prepare a cDNA library. After prescreening, clones containing somatostatin I sequences were identified by hybridization with an anglerfish somatostatin I-cloned cDNA probe. From the nucleotide sequence of two of these clones, we have deduced an essentially full-length mRNA sequence, including the preprosomatostatin coding...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1988
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/16.24.11818